6/10/2023 0 Comments Dynamic light scattering machineThis makes it an ideal analytical technique for high value or early stage development testing and final quality control. Dynamic light scattering (DLS), sometimes referred to as Quasi Elastic Light Scattering (QELS), is a non-invasive, well-established technique for measuring the size and size distribution of molecules and particles typically in the submicron region, and with the latest technology, lower than 1nm. Only a small sample size is required (typically 1ml suspension in a cuvette) and the equipment can deal with a range of active concentrations with measurement time only requiring a few minutes. By monitoring the intensity of the scattered light versus time at a fixed angle, this data can be mathematically converted to a nanoparticle size and distribution within the sample. A laser is fired through the sample and the light is scattered by suspended particles. The sample is suspended in a solution to give slight turbidity. Slurry control – wanted or unwanted flocculation / sedimentation.Controlled formation of larger materials with specific properties.Increasing the available power in batteries.Nanoparticle use in targeted oncology treatments Dynamic light scattering: a practical guide and applications in biomedical sciences Biophys Rev.Nanoparticles are a focus area for many industries, potential applications include: When laser light illuminates particles under the influence of Brownian motion. This information supports research and development in drug delivery and consumer products such as shampoos and toothpastes, to give just two examples. The motion is slower with larger particles and faster with smaller particles. Such arrangements alter with surfactant concentration and the concentration of simple electrolyte ions present. As well as solid particles, DLS is invaluable for “seeing” how surfactant molecules arrange together as micellar structures. ![]() This technique is particularly useful to study the behavior of nanoparticles in suspensions.Ĭombined with zeta potential information, DLS data, versus time, provides insights into (for example) the tendency for nanoparticles to agglomerate. Simple, versatile dynamic light scattering system - Zetasizer Nano Supported products Zetasizer Nano ZSP Sensitivity, simplicity, versatility Measurement Molecular size Particle size Molecular weight Zeta potential Protein mobility Microrheology Particle size range 0. Dynamic Light Scattering (DLS) analysis allows us to confidently measure the size distribution profiles of particles in the sub-micron range.
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